and the (4-7) head to the West Coast to take on and the red-hot (6-4) on Sunday afternoon at Levi's Stadium. The Saints are coming off a 27-20 win over the defending champion , while the 49ers are looking to win their fourth straight after blowing out the 38-10 on Monday Night Football in Mexico City. New Orleans is 4-7 against the spread, while San Francisco is 5-5 ATS in 2022.Kickoff is at 4:25 p.m. ET. San Francisco is favored by 9 points in the latest 49ers vs. Saints odds from Caesars Sportsbook, and the Yoenis Cespedes Jersey over/under is set at 43.5. Before entering any Saints vs. 49ers picks, .The model, which simulates every game 10,000 times, is up well over $7,000 for $100 players on top-rated since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on top-rated that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL Mookie Wilson Jersey picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.Now, the model has set its sights on and just locked in its picks and NFL Week 12 predictions. . Here are several for Saints vs. 49ers:49ers vs. Saints spread: 49ers -949ers vs. Saints over/under: 43.5 points49ers vs. Saints money line: San Francisco -440, New Orleans +33549ers vs. Saints picks: Featured Game | San Francisco 49ers vs. New Orleans Saints Moneyline Spread Total SF NO The 49ers were dominant in their 38-10 win over the Cardinals on Monday Jeff McNeil Jersey Night Football. Quarterback Jimmy Garoppolo completed 20 of 29 pa ses for 229 yards and four touchdowns. All-Pro tight end hauled in four pa ses for 84 yards and two TDs, while wide receiver caught two pa ses for 20 yards with both going for touchdowns.Since acquiring , the 49ers have gone 3-1 and now look like a legitimate threat to represent the NFC in Super Bowl LVII. San Francisco was widely regarded as the league's best defensive team, and now Garoppolo Amed Rosario Jersey has arguably the NFL's best arsenal of weapons at his disposal in McCaffrey, Kittle, Aiyuk, , and .Meanwhile, New Orleans secured a 27-20 victory over the Los Angeles Rams this past Sunday. Dalton pa sed for three TDs and 260 yards on 25 attempts. Dalton's 53-yard touchdown to s up the middle to WR in the third quarter made for one of the most memorable moments of the afternoon.The Saints could get a much-needed boost this week with cornerback (abdomen), cornerback , defensive end (eye), defensive end (calf), left guard (triceps), left tackle (concu Pete Alonso Jersey sion) and running back (knee) all returning to practice this week. They are all listed as questionable, with several expected to play on Sunday.The model has simulated Saints vs. 49ers 10,000 times and the results are in. The model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. .So who wins Saints vs. 49ers? And which side of the spread hits well over 50% of the time? , and find out.
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